Huperzine A

 Huperzine A is an alkaloid extracted from a plant called Chinese lycopodium (Melaleuca pylon). Chinese stone pine has traditionally been used to treat bruises, rheumatism, fever and colds, and to improve blood circulation.

In 1948, Huperzine A was isolated in China and the United States, respectively.

Currently, it is a medicine in China and a food supplement (health supplement) in the United States.

 Preliminary research shows that:

Huperzine A may improve memory and life functions in Alzheimer's patients. However, cholinesterase inhibitor drugs whose efficacy and safety have been tested are more reliable.

Huperzine A may also be helpful for memory function in people and adolescents with conditions such as multi-infarct dementia or Alzheimer's disease.

Huperzine A appears to be beneficial in myasthenia gravis.

Larger, well-established clinical trials are needed to confirm its efficacy and long-term safety. Existing studies are small in scale and of low quality.

Other uses: age-related memory loss, cognitive function in Alzheimer's disease, brain trauma, organic mental disorders, motor muscle trauma, diabetic neuropathy, acute and chronic Achilles tendon pain, organophosphate poisoning, etc. lack of scientific evidence.

Huperzine A appears to be safe for short-term use.

Adverse reactions include hyperactivity, nasal congestion, nausea, vomiting, diarrhea, insomnia, anxiety, dizziness, thirst, constipation, myocardial ischemia and bradycardia.

Toxicity: Acute symptoms include muscle tremors, salivation, lacrimation, increased bronchial secretions, and urinary incontinence.

Contraindications: Pregnant or breastfeeding

Children: Arrhythmia or angina

Epilepsy: inflammatory bowel disease or mechanical bowel obstruction

Bronchial asthma or chronic obstructive pulmonary disease

Urinary or reproductive system obstruction

Drug interactions (including herbal and health products, etc.):

Anticholinergics: Co-agents should be used with caution.

Cholinergic Drugs: Co-agents should be used with caution.

Acetylcholinesterase Inhibitors: Co-agents should be used with caution.